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Psych Congress  

An Experimental Study to Assess the Professional and Social Consequences of Tardive Dyskinesia


Rajeev Ayyagari, PhD – Analysis Group, Inc.; Debbie Goldschmidt, PhD – Analysis Group, Inc.; Fan Mu, PhD – Analysis Group, Inc.; Stanley Caroff, MD – Corporal Michael J. Crescenz VA Medical Center; University of Pennsylvania Perelman School of Medicine; Benjamin Carroll, PharmD – Teva Pharmaceuticals

Teva Pharmaceuticals

BACKGROUND: Tardive dyskinesia (TD), a movement disorder that can develop in patients taking antipsychotics, is a potential source of stigma, but this has not been thoroughly examined. Here, we evaluate the impact of moderate-to-severe orofacial TD symptoms on the professional and social lives of patients.

DESIGN/METHODS: This study was an experimental, randomized digital survey of a general population sample. Three component surveys were developed, corresponding to employment, dating, and friendship domains. For each domain, participants were randomized 1:1 into either a test group (who viewed a video of an actor depicting moderate-to-severe TD movements) or a control group (who viewed the same actor but without TD movements) and asked about their impressions of the video subject.

RESULTS: 800 participants completed each survey. In all domains, participants responded less favorably to the actor when portraying moderate-to-severe TD movements than without the movements. Fewer participants in the test group, versus the control group, thought the actor “would be suitable for client-facing jobs” (34.8% fewer in the test group [P < 0.001]), were “interested in meeting them for a coffee/drink” (27.2% fewer in the test group [P < 0.001]), and felt like the actor “seemed to be an interesting person” (18.8% fewer in the test group [P < 0.001]) in the employment, dating, and friendship domains, respectively.

CONCLUSIONS: Actors simulating moderate-to-severe TD movements were perceived more negatively than those without TD movements in employment, dating, and friendship domains. To our knowledge, this is the first study to quantify the stigma people with TD face in professional and social situations.

This poster was presented at the 32nd annual Psych Congress, held Oct. 3-6, 2019, in San Diego, California.

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