Alzheimer’s Disease, Dementia & Cognitive Disorders

Three rare genetic variants are associated with Alzheimer's disease (AD), according to new findings from the Alzheimer's Disease Sequencing Project (ADSP).


lmost half of U.S. Medicare beneficiaries with Parkinson's disease (PD) and dementia are prescribed medications that should never be given together, according to a study presented at the 2018 Annual Meeting of the American Neurological Association (ANA) in Atlanta.

Elevated levels of neurofilament light (NfL) protein in cerebrospinal fluid (CSF) are associated with increased risk for mild cognitive impairment (MCI) in older cognitively normal adults, new research suggests.

Concomitant use of cholinesterase inhibitors or memantine is associated with quicker cognitive decline in patients participating in Alzheimer clinical trials, according to a meta-analysis.

Head injury appears to be linked with a higher risk of long-term cognitive decline and dementia in community-dwelling adults, according to a new study.

Pregnant women who develop preeclampsia have more than three times higher risk of dementia later in life than women who don't have this pregnancy complication, researchers say.



Money spent by the National Institutes of Health on Alzheimer’s disease research has actually decreased in recent years, and total research for Alzheimer’s disease is less than one-fifth of that for cancer and heart disease, respectively.

Although we often assume that the impact of trauma manifests right away, sometimes it can manifest decades later. This phenomenon was commonly seen in many World War II veterans who first began to experience PTSD symptoms around the time of fiftieth anniversary commemorations of the war in the mid-1990s.

Too often, physicians assume that the baseline diagnosis of Alzheimer's disease is correct and proceed accordingly. But is every case of presumptive cognitive impairment actually Alzheimer’s disease?



Kenneth Rockwood, MD; Myrlene Aigbogun, MPH; Justin Stanley, BS; Helen Wong, MSc; Taylor Dunn, BS; Chere Chapman, MBA, MHSc; Maia Miguelez, PhD; Ross Baker, PhD, MBA
Andrew Valadez, BS; Rustin Berlow, MD
Milena Anatchkova, PhD; Anne Brooks, BS; Laura Swett, PhD; Ann Hartry, PhD; Ruth Duffy, PhD; Ross Baker, PhD, MBA; Myrlene Aigbogun, MPH
Rachel Halpern, PhD; Jerry Seare, MD; Junliang Tong, MS, MA; Ann Hartry, PhD; Anthony Olaoye, MBA, MS; Myrlene Aigbogun, MPH



In a new study published in JAMA, researchers examined the brains of 202 deceased former football players—more than half of them from the National Football League (NFL)—for signs of chronic traumatic encephalopathy (CTE).

A new study suggests people may be able to lower their risk of developing mild cognitive impairment by engaging in mentally stimulating activities later in life.

Peter Weiden, MD, and Charles Raision, MD, talk about how to do cognitive behavioral therapy with a group of people who have patterns of cognitive dysfunction. Click here to read the