Bipolar Disorders

Valbenazine significantly reduced involuntary movements associated with tardive dyskinesia in patients with primary mood disorders, at both 6 weeks and 48 weeks after beginning the treatment, according to a published analysis.

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The nutraceutical creatine monohydrate was associated with increased verbal fluency scores, when used as an adjunctive treatment in a small study on patients with bipolar depression.

Concentrations of C-reactive protein (CRP) are higher in people diagnosed with bipolar disorder, compared with healthy controls, according to a systematic review and meta-analysis published online in The Lancet Psychiatry.

In bipolar depression, adjunctive second-generation antidepressants work, but not very well, and their efficacy and safety remain controversial, according to results of a new systematic review and meta-analysis.

Structural deficits may explain cognitive difficulties experienced by patients with bipolar disorder even during periods of normal mood, according to a study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.

One in 5 patients with bipolar disorder also has borderline personality disorder, and identifying both in the same patient can be tricky, Mark Zimmerman, MD, told attendees at Psych Congress.

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