Depression

Novel Dextromethorphan-Bupropion Tablet Rapidly Improves Depressive Symptoms
AXS-05, an investigational modulated-delivery tablet combining dextromethorphan and bupropion, significantly improved symptoms of depression in patients with major depressive disorder (MDD) in a recent phase 3 trial, announced developer Axsome Therapeutics Inc.
Adjunctive L-Methylfolate Offers Benefit in Depression Treatment
Supplemental treatment with the medical food L-methylfolate may benefit patients with depression who do not respond to antidepressants, according to a review article published online in CNS Spectrums.
Cannabis Use Twice as Common Among People With Depression
Although the prevalence of cannabis use in the United States grew among people with and without depression between 2005 and 2017, in 2017 cannabis use was twice as common among people with depression.
Structural Differences Seen in Brains of Children With a Depressed Parent
Having a parent with depression was associated with structural differences in the brains of 9- and 10-year-olds, according to a study published online in the Journal of the American Academy of Child & Adolescent Psychiatry.
Despite Antidepressants, Suicidal Ideation Affects 1 in 5 People With MDD
Approximately 20% of people with major depressive disorder (MDD) experienced high or fluctuating suicidal ideation over 12 weeks of treatment with antidepressants, researchers found in a study published in The Journal of Clinical Psychiatry.
Mental Health Issues in Others May Drive People to Seek Depression Treatment
Knowing someone with emotional or mental health problems increased the likelihood that people who screened positive for depression sought out depression treatment for themselves, according to a study published online in Psychiatric Services.
Using Antipsychotics as an Adjunctive Therapy in Depression
Michael Thase, MD, discusses the use of second-generation antipsychotics as an adjunctive therapy in depression.
Combining Antidepressants When Treating Depression
Michael Thase, MD, provides details on the strategy of combining antidepressants when treating patients with depression.
Cannabinoids Not Justified as Mental Health Treatment, Study Says
A meta-analysis recently published in The Lancet Psychiatry found that using medicinal cannabinoids to treat mental health disorders cannot be justified, due to a lack of evidence of effectiveness and known risks of the substances.
Teen Depression Risk Lower in Close-Knit Families
Teens with positive family relationships may be less likely to develop depression during adolescence or early adulthood, a new study suggests.
Oral Contraceptives Linked to Depressive Symptoms in Teens
Teenage users of oral contraceptive pills (OCP), particularly 16-year-olds, had higher concurrent depressive symptoms than their nonuser peers in an observational study.

Videos

Clay Jackson
Treatment Approaches for Patients With Depression and Substance Use Disorders
W. Clay Jackson, MD, DipTh, of the University of Tennessee College of Medicine in Memphis, discusses treatment approaches for patients with depression and substance use disorders.
Michael Thase, MD
Using Antipsychotics as an Adjunctive Therapy in Depression
Michael Thase, MD
Combining Antidepressants When Treating Depression
Detecting Mixed Features in Major Depression

Audio

ABC News Podcast Features Psych Congress Faculty
Two members of the Psych Congress Steering Committee have been featured on an ABC News podcast which grew out of a newsman's newfound interest in meditation.
A Discussion on the Science of Depression
Listen as Psych Congress Steering Committee member Charles Raison, MD, discusses a book he coauthored, The New Mind-Body Science of Depression, with David Van Nuys, PhD, on Shrink Rap Radio.
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