Adjunctive testosterone treatment in men is associated with a significant drop in depressive symptoms, compared with placebo, according to a systematic review and meta-analysis published online in JAMA Psychiatry.


The antidepressant vilazodone reduced depressive symptoms in patients with characteristics previously linked with reduced response to antidepressants, researchers reported in International Clinical Psychopharmacology.

Children with autism who also have attention deficit hyperactivity disorder (ADHD) are more likely to develop anxiety and depression than autistic kids without ADHD, a U.S. study suggests.

Preschool-aged children are more likely to be injured if their mothers report depressive symptoms during or after pregnancy, according to a new study in Injury Prevention.

Alkermes Plc has been told to conduct more clinical trials of its experimental depression treatment after the FDA rejected its initial application for approval, citing a lack of evidence of its effectiveness.

abnormal brain

A longitudinal study published in JAMA Psychiatry revealed a significant association between relapse in major depressive disorder (MDD) and loss of volume in certain parts of the brain.



Carl Gommoll, MS. Richard Chen, PhD. Alix Bennett, PhD. Leslie Citrome, MD.