More frequent in-person social interaction is linked with a significantly lower risk of symptoms of major depression and posttraumatic stress disorder (PTSD) in US military veterans, according to a study published online.


Women who have asthma during their pregnancies are more likely to experience postpartum depression after delivery, a large Canadian study suggests.

People with depression or bipolar disorder were found to have a larger hypothalamus, compared with healthy control subjects, in a study published in Acta Psychiatrica Scandinavia.

Did you know?

A recently published study involving 916 patients found which clinical factor to be the most prominent predictor of treatment-resistant depression?

MRI-based predictive tools could inform therapeutic decision making, potentially preventing functional impairment in patients at high clinical risk of psychosis and those with recent-onset depression, researchers say.

With the exception of paroxetine, the long-term use of most antidepressants does not increase dementia risk, suggests a study published in the Journal of the American Geriatrics Society.



Approximately 750 of our fellow physicians, nurses, psychotherapists take their own lives each year, making it imperative that we begin to explore and understand the despair within our ranks.

In our world of ever-expanding pharmacologic options, we continue to see patients whose treatment may be compromised by non-adherence to our prescribed medication regimens.

Even 4 or 5 years ago, the future of depression treatment was coming toward us, but it was far enough off to look uncertain. Now, the future is almost here, close enough at least for us to begin getting a sense of what the general outlines will be.



Karen Anderson, MD; Mat Davis, PhD; Stewart Factor, DO; Robert Hauser, MD, MBA; Lars Jarskog, MD; Joohi Jimenez-Shahed, MD; Rajeev Kumar, MD, FRCPC; Stanislaw Ochudlo, MD, PhD; William Ondo, MD; Hubert Fernandez, MD
Jyotsna Mehta, B.Pharm, MS; Xiaowu Sun, PhD; Asli Memisoglu, MS, ScD; Arielle Stanford, MD; Nikki Levy, BS; Mugdha Gore, B.Pharm, PhD
Alexandra Kuzman, DNP; Quiping Zhou, PhD; Jose Vazquez, MD
Carmela Benson, MS; Ahong Huang, MS; Li Wang, MA, PhD, MBA; Neeta Tandon, MA, PhD; Abigail Nash, PhD, MD; Onur Baser, MS, PhD
Donna Cox, PhD; Micha Levi, PhD; Laura Rabinovich, PhD; David Truong, PharmD, MS; David Stamler, MD



David E. Nichols, PhD, talks with Charles Raison, MD, about how ketamine works at the receptor level to produce powerful and rapid antidepressant effects. Click through to watch the video and read a transcript.

Charles Raison, MD, interviews Gerard Sanacora, MD, PhD, about a common clinical scenario—a patient in your office requests ketamine, an experimental treatment. What do you do?