Major Depressive Disorder

A new cohort study confirmed a previously reported association between treatment with antidepressants and hip fracture in older adults, but it contained a twist.


Fathers’ depression during the postnatal period was associated with depression in their daughters 18 years later, researchers found.

Sage Therapeutics Inc's oral treatment for postpartum depression met the main goal of reducing symptoms of the condition, when compared with a placebo in a phase 3 clinical trial.

Teenage girls are twice as likely as boys to show depressive symptoms linked to social media use - mainly due to online harassment and disturbed sleep, as well as poor body image and lower self-esteem, researchers have found.

Anxiety and depression are as predictive of poor physical health as obesity and smoking are and, consequently, should be better addressed during routine visits to primary care providers, suggests a study published online in Health Psychology.

In abstinence-motivated people with opioid dependence, symptoms of anxiety, depression or insomnia should not prevent switching from an opioid agonist to extended-release naltrexone (XR-NTX), researchers in Norway say.



BLOG: On January 18, 2018, in Sacramento California, new mother Jessica Porten went to see a women’s health nurse practitioner. She was 4 months postpartum and had not been seen by her obstetric provider since giving birth.

BLOG: Recent qualitative studies on subjects treated with psilocybin may begin to help us understand the subjective experience caused by the drug that may lead to its antidepressant effects.

BLOG: We psychiatrists read so much about physicians being “difficult patients.” What about when the shoe is on the other foot?



Rikinkumar Patel, MD, MPH; Mandeep Kaur, MD; Ahmed Elmaadawi, MD; Zeeshan Mansuri, MD, MPH; Kaushal Shah, MBBS, MPH; Suhayl Nasr, MD
Joseph Goldberg, MD; Cynthia Siu, PhD; Yongcai Mao, PhD; Joyce Tsai, PhD; Andrei Pikalov, MD, PhD; Joseph Calabrese, MD; Antony Loebel, MD
Karen Anderson, MD; Mat Davis, PhD; Stewart Factor, DO; Robert Hauser, MD, MBA; Lars Jarskog, MD; Joohi Jimenez-Shahed, MD; Rajeev Kumar, MD, FRCPC; Stanislaw Ochudlo, MD, PhD; William Ondo, MD; Hubert Fernandez, MD
Stanley Caroff, MD; Fan Mu, PhD; Rajeev Ayyagari, PhD; Traci Schilling, MD; Victor Abler, DO; Benjamin Carroll, PharmD



Jon-Kar Zubieta, MD, PhD, discusses the potential role of the endogenous opioid system in MDD.

Andrew J. Cutler, MD, discusses evolving theories in MDD pathophysiology and challenges of patient management.



Listen as Psych Congress Steering Committee member Charles Raison, MD, discusses a book he coauthored, The New Mind-Body Science of Depression, with David Van Nuys, PhD, on Shrink Rap Radio.