Major Depressive Disorder

A new cohort study confirmed a previously reported association between treatment with antidepressants and hip fracture in older adults, but it contained a twist.


antipsychotic medications

A meta-analysis of trials of antipsychotic medications suggests that although antipsychotics are linked with small-to-moderate improvement in symptoms of depression, they do not seem to improve patients’ quality of life.

nutrition program

Patients with dementia who engage in an individualized program that teaches proper eating habits show reduced symptoms of depression, researchers reported in the online February 28 Journal of Advanced Nursing.

Psychiatric Disorders DNA

Five major psychiatric disorders—autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia—share underlying genetic variants, according to the results of a genome-wide analysis published in the online February 28 Lancet.

herpes zoster vaccine

The herpes zoster vaccine is less effective in patients with untreated depression, but treatment with antidepressant medications can normalize patients’ immune responses, according to a longitudinal cohort study published in the online February 13 Clinical Infectious Diseases.


Patients with major depressive disorder show improvement when treated with a combination of transcranial direct current stimulation and sertraline, according to a double-blind, controlled trial published in the online February 6 JAMA Psychiatry.