Major Depressive Disorder

A new cohort study confirmed a previously reported association between treatment with antidepressants and hip fracture in older adults, but it contained a twist.


Patients who are treated in an intensive care unit (ICU) and survive are at increased risk of depression, a new study suggests. And depression in ICU survivors was linked with a higher risk of death in the next two years, researchers found.

The increased likelihood of depression in people with obesity stems from the psychological effect of being overweight and not only from associated illnesses such as diabetes, a study suggests.

People who survive car crashes, falls, and other major traumas that require hospitalization are at increased risk of developing mental health conditions and dying by suicide, according to a study published online.

Rakesh Jain, MD, MPH

Is there benefit in treating a patient with a VMAT2 inhibitor if they have already had severe tardive dyskinesia for several years? Find out here.

Using brain imaging, researchers have identified three distinct neurophysiological subtypes of depression—one of which does not respond to treatment with selective serotonin-reuptake inhibitors.



Approximately 750 of our fellow physicians, nurses, psychotherapists take their own lives each year, making it imperative that we begin to explore and understand the despair within our ranks.

In our world of ever-expanding pharmacologic options, we continue to see patients whose treatment may be compromised by non-adherence to our prescribed medication regimens.

Even 4 or 5 years ago, the future of depression treatment was coming toward us, but it was far enough off to look uncertain. Now, the future is almost here, close enough at least for us to begin getting a sense of what the general outlines will be.



Karen Anderson, MD; Mat Davis, PhD; Stewart Factor, DO; Robert Hauser, MD, MBA; Lars Jarskog, MD; Joohi Jimenez-Shahed, MD; Rajeev Kumar, MD, FRCPC; Stanislaw Ochudlo, MD, PhD; William Ondo, MD; Hubert Fernandez, MD
Jyotsna Mehta, B.Pharm, MS; Xiaowu Sun, PhD; Asli Memisoglu, MS, ScD; Arielle Stanford, MD; Nikki Levy, BS; Mugdha Gore, B.Pharm, PhD
Alexandra Kuzman, DNP; Quiping Zhou, PhD; Jose Vazquez, MD
Carmela Benson, MS; Ahong Huang, MS; Li Wang, MA, PhD, MBA; Neeta Tandon, MA, PhD; Abigail Nash, PhD, MD; Onur Baser, MS, PhD
Donna Cox, PhD; Micha Levi, PhD; Laura Rabinovich, PhD; David Truong, PharmD, MS; David Stamler, MD



Psych Congress Steering Committee members Jon W. Draud, MD, MS, and Saundra Jain, MA, PsyD, LPC, discuss the use of transcranial magnetic stimulation (TMS) on patients with treatment-resistant depression.

Gerard Sanacora, MD, PhD, and Charles Raison, MD, talk about considerations surrounding the decision to prescribe ketamine, an experimental therapeutic, to patients struggling with depression.

Psych Congress Steering Committee members Vladimir Maletic, MD, MS, and Jon W. Draud, MD, MS, discuss the clinical consequences of misdiagnosing mixed mood states.